Precocious puberty in a female with Proteus Syndrome

Authors

• Kamal M. Ezzeldin, Department of Radiology, PO Box 1051, Al-Hada Armed Forces Hospital, Taif, Kingdom of Saudi Arabia. Tel. +966 (2) 7541610. Fax +966 (2) 7541238. E-mail: kamalezzeldin{at}hot mail.com
• Asmaa A. Ezzeldin, Department of Pediatrics, Alnoor Specialist Hospital, Makkah, Kingdom of Saudi Arabia.
• Ahmad J. Zahrani, Department of Pediatrics, Alnoor Specialist Hospital, Makkah, Kingdom of Saudi Arabia.
• Maher M. Al-Zaiem, Department of Pediatric Surgery, Alnoor Specialist Hospital, Makkah, Kingdom of Saudi Arabia.

Abstract

Proteus syndrome is a complex disorder comprising malformations and overgrowth of multiple tissues and characterized by its polymorphism and mosaicism. The syndrome is rare and sporadic. Oliveira M da C et al1 reported the first case of Proteus syndrome associated with precocious puberty in a boy. We are reporting a case of a 7-month old girl with Proteus syndrome who developed a juvenile granulosa cell tumor in one ovary causing precocious puberty. At our knowledge this is the first case of Proteus syndrome with precocious puberty in a female.

Article Type

Case Report

First Page

332

Last Page

334

Recommended Citation

Ezzeldin, Kamal M.; Ezzeldin, Asmaa A.; Zahrani, Ahmad J.; and Al-Zaiem, Maher M. (2002) "Precocious puberty in a female with Proteus Syndrome," Saudi Medical Journal: Vol. 23: Iss. 3, Article 17.
DOI: https://doi.org/10.15537/1658-3175.1654