Acute myeloblastic leukemia in a patient with primary antiphospholipid syndrome

Authors

• Shiv K. Saxena, Consultant Physician and Chairman, Department of Medicine, Al Iman General Hospital, Ministry of Health, PO Box 346225, Riyadh 11381, Kingdom of Saudi Arabia. Tel. +966 (1) 4174043/57130233/2520088 Ext. 4167. Fax. +966 (1) 4471917. E-mail: shivksaxena{at}yahoo.com
• Ahmed H. Al-Jizeeri, Department of Medicine, King Abdul-Aziz Medical City, Riyadh, Kingdom of Saudi Arabia.
• Osman A. Kheir, Department of Medicine, King Abdul-Aziz Medical City, Riyadh, Kingdom of Saudi Arabia.

Abstract

Antiphospholipid syndrome is characterized by venous and arterial thrombosis, recurrent pregnancy loss and the presence of the lupus anticoagulant, anticardiolipin antibodies or both. Antiphospholipid syndrome may occur as a primary disease or in patients with systemic lupus erythematosus or other autoimmune, infectious or neoplastic disorders. In this paper we report a 29-year-old Saudi female, a known case of antiphospholipid syndrome, presented with complaints of fever, breathlessness and generalized fatigue. Further investigations confirmed her as a case of myeloblastic leukemia (M1, French-American-British classification). Acute myeloblastic leukemia is not described to be associated with primary antiphospholipid syndrome in the literature to date. This is the first case report of such association.

Article Type

Case Report

First Page

1013

Last Page

1015

Recommended Citation

Saxena, Shiv K.; Al-Jizeeri, Ahmed H.; and Kheir, Osman A. (2003) "Acute myeloblastic leukemia in a patient with primary antiphospholipid syndrome," Saudi Medical Journal: Vol. 24: Iss. 9, Article 21.
DOI: https://doi.org/10.15537/1658-3175.2167