Renal abnormalities in congenital chloride diarrhea

Authors

• Nadia M. Al-Hamad, Department of Pediatrics, Mubarak Al-Kabeer Hospital, Ministry of Health, Safat, Kuwait.
• Amal A. Al-Eisa, Department of Pediatrics, Faculty of Medicine, Kuwait University, PO Box 24923 Safat 13110, State of Kuwait. Tel. +965 5319486. Fax. +965 5338940. E-mail: amal{at}hsc.kuniv.edu.kw.

Abstract

Congenital chloride diarrhea CLD is a rare autosomal recessive disorder caused by a defect in the chloride/ bicarbonate exchange in the ileum and colon. It is characterized by watery diarrhea, abdominal distension, hypochloremic hypokalemic metabolic alkalosis with high fecal content of chloride >90 mmol/l. We report 3 patients with CLD associated with various renal abnormalities including chronic renal failure secondary to renal hypoplasia, nephrocalcinosis and congenital nephrotic syndrome.

Article Type

Case Report

First Page

651

Last Page

655

Recommended Citation

Al-Hamad, Nadia M. and Al-Eisa, Amal A. (2004) "Renal abnormalities in congenital chloride diarrhea," Saudi Medical Journal: Vol. 25: Iss. 5, Article 20.
DOI: https://doi.org/10.15537/1658-3175.2417