Apoptosis and eosinophils. Regulation and clinical relevance

Authors

• Faris Q Alenzi،, Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, PO Box 422, Al-Kharaj 11942, Kingdom of Saudi Arabia. E-mail: falenzi{at}ksu.edu.sa

Abstract

Apoptosis, or program cell death, is a process of fundamental biological importance, and eosinophil apoptosis is believed to be the primary mechanism for removing eosinophils from the lung followed by their recognition and phagocytosis by macrophages or resident bronchial epithelial cells. There is, therefore, an increased interest in the fundamental role of the signals and intracellular signaling molecules that initiate and control apoptosis in human eosinophils though much remains to be established. This article reviews briefly the cross talks between apoptosis and eosinophils and summarizes the recent developments in this field.

Article Type

Review

First Page

643

Last Page

656

Recommended Citation

Alenzi،, Faris Q (2008) "Apoptosis and eosinophils. Regulation and clinical relevance," Saudi Medical Journal: Vol. 29: Iss. 5, Article 1.
DOI: https://doi.org/10.15537/1658-3175.4317