Progeria with post-streptococcal glomerulonephritis. A rare case report with differential diagnosis

Authors

• Alphy A. Sebastian, Department of Oral Medicine and Radiology, St. Gregorios Dental College, Kothamangalam, Kerala 686681, India. Tel. +91 (974) 4267536. Fax. +91 (485) 2572530. E-mail: alphyalphonsa1{at}yahoo.com
• Auswaf K. Ahsan, Department of Oral Medicine and Radiology, St. Gregorios Dental College, Kothamangalam, Kerala 686681, India. Tel. +91 (974) 4267536. Fax. +91 (485) 2572530. E-mail: alphyalphonsa1{at}yahoo.com

Abstract

Hutchinson-Gilford progeria syndrome is a rare autosomal dominant disorder associated with skin fragility. It is characterized by craniofacial disproportion, delayed dentition, micrognathia, and plucked bird appearance. The genetic defect is mainly de nova mutation in the lamin A gene. This report describes a 16-year-old patient with classical features of progeria along with post-streptococcal glomerulonephritis. The symptoms of hepatomegaly were also present in the patient. The differential diagnoses of this lesion are also discussed in detail in this literature.

Article Type

Case Report

First Page

190

Last Page

194

Recommended Citation

Sebastian, Alphy A. and Ahsan, Auswaf K. (2013) "Progeria with post-streptococcal glomerulonephritis. A rare case report with differential diagnosis," Saudi Medical Journal: Vol. 34: Iss. 2, Article 13.
DOI: https://doi.org/10.15537/1658-3175.5712