Malignant transformation of persistent endometriosis after hysterectomy

Authors

• Naif A. Bawazeer, Faculty of Medicine, Umm Alqura University, PO Box 1129, Makkah 21955, Kingdom of Saudi Arabia. Tel. +966 (12) 5556644. E-mail. naifbm{at}hotmail.com
• Hatim M. Al-Jifree, Faculty of Medicine, Umm Alqura University, PO Box 1129, Makkah 21955, Kingdom of Saudi Arabia. Tel. +966 (12) 5556644. E-mail. naifbm{at}hotmail.com
• Abdulrahim M. Gari, Faculty of Medicine, Umm Alqura University, PO Box 1129, Makkah 21955, Kingdom of Saudi Arabia. Tel. +966 (12) 5556644. E-mail. naifbm{at}hotmail.com

Abstract

The malignant transformation of persistent endometriotic implants into endometrioid adenocarcinoma is rare, especially after remote hysterectomy and salpingo-oophorectomy (TAH-BSO), and there are few cases reported in the English language literature. Patients receiving estrogen replacement therapy are common among the reported cases. We present a case that demonstrates the possibility of malignant transformation in a 53-year-old female, known case of endometriosis, who underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy with no evidence of malignancy in the final pathology report. After 9 years, she presented with lower abdominal mass, and histopathological studies confirmed the diagnosis of well-differentiated endometrioid adenocarcinoma. The possibility of malignant transformation and possible risk factors are discussed with a brief literature review.

Article Type

Case Report

First Page

1390

Last Page

1392

Recommended Citation

Bawazeer, Naif A.; Al-Jifree, Hatim M.; and Gari, Abdulrahim M. (2014) "Malignant transformation of persistent endometriosis after hysterectomy," Saudi Medical Journal: Vol. 35: Iss. 11, Article 13.
DOI: https://doi.org/10.15537/1658-3175.6084