Diabetes mellitus in two genetically distinct populations in Jordan: A comparison between Arabs and Circassians/Chechens living with diabetes

Authors

• Laith N. Al-Eitan, From the Departments of Applied Biological Sciences, Biotechnology and Genetic Engineering (Al-Eitan), Department of Clinical Pharmacy (Almomani), Department of Internal Medicine (Saadeh), Jordan University of Science and Technology, Irbid, Hematopoietic and Stem Cell Transplantation Center (Nassar), Istishari Hospital, Amman, and the Department of Biology and Biotechnology (Dajani), The Hashemite University, Zarqa, Jordan
• Ahmad M. Nassar, From the Departments of Applied Biological Sciences, Biotechnology and Genetic Engineering (Al-Eitan), Department of Clinical Pharmacy (Almomani), Department of Internal Medicine (Saadeh), Jordan University of Science and Technology, Irbid, Hematopoietic and Stem Cell Transplantation Center (Nassar), Istishari Hospital, Amman, and the Department of Biology and Biotechnology (Dajani), The Hashemite University, Zarqa, Jordan
• Rana B. Dajani, From the Departments of Applied Biological Sciences, Biotechnology and Genetic Engineering (Al-Eitan), Department of Clinical Pharmacy (Almomani), Department of Internal Medicine (Saadeh), Jordan University of Science and Technology, Irbid, Hematopoietic and Stem Cell Transplantation Center (Nassar), Istishari Hospital, Amman, and the Department of Biology and Biotechnology (Dajani), The Hashemite University, Zarqa, Jordan
• Basima A. Almomani, From the Departments of Applied Biological Sciences, Biotechnology and Genetic Engineering (Al-Eitan), Department of Clinical Pharmacy (Almomani), Department of Internal Medicine (Saadeh), Jordan University of Science and Technology, Irbid, Hematopoietic and Stem Cell Transplantation Center (Nassar), Istishari Hospital, Amman, and the Department of Biology and Biotechnology (Dajani), The Hashemite University, Zarqa, Jordan
• Nesreen A. Saadeh, From the Departments of Applied Biological Sciences, Biotechnology and Genetic Engineering (Al-Eitan), Department of Clinical Pharmacy (Almomani), Department of Internal Medicine (Saadeh), Jordan University of Science and Technology, Irbid, Hematopoietic and Stem Cell Transplantation Center (Nassar), Istishari Hospital, Amman, and the Department of Biology and Biotechnology (Dajani), The Hashemite University, Zarqa, Jordan

Abstract

Objectives: To compare clinical, anthropometric, and laboratory characteristics in diabetes type 2 patients of 2 genetically-distinct ethnicities living in Jordan, Arabs and Circassians/Chechens. Methods: This cross sectional ethnic comparison study was conducted in King Abdullah University Hospital, Irbid and The National Center for Diabetes, Endocrinology, and Genetics, Amman, Jordan between June 2013 and February 2014. A sample of 347 (237 Arab and 110 Circassian/Chechen) people living with diabetes were included in the study. Data were collected through direct interviews with the participants. Clinical data were collected using a questionnaire and anthropometric measurements. Laboratory data were extracted from the patients’ medical records. Results: More Arabs with diabetes had hypertension as a comorbidity than Circassians/Chechens with diabetes. Arabs living with diabetes were generally more obese, whereas Circassians/Chechens living with diabetes had worse lipid control. Arabs with diabetes had higher means of glycated haemoglobin (HbA1c) and fasting blood sugar, and more Arabs with diabetes had unsatisfactory glycemic control (60.6%) than Circassians/Chechens with diabetes (38.2%) (HbA1c ≥7.0%). Most participants (88.8%) had at least one lipid abnormality (dyslipidemia). Conclusion: Multiple discrepancies among the 2 ethnic diabetic populations were found. New diabetes management recommendations and policies should be used when treating people living with diabetes of those ethnicities, particularly in areas of glycemic control, lipid control, and obesity.

Article Type

Research Article

First Page

163

Last Page

169

Recommended Citation

Al-Eitan, Laith N.; Nassar, Ahmad M.; Dajani, Rana B.; Almomani, Basima A.; and Saadeh, Nesreen A. (2017) "Diabetes mellitus in two genetically distinct populations in Jordan: A comparison between Arabs and Circassians/Chechens living with diabetes," Saudi Medical Journal: Vol. 38: Iss. 2, Article 8.
DOI: https://doi.org/10.15537/smj.2017.2.17910