The role of non-invasive ventilation used immediately after planned extubation for adults with chronic respiratory disorders

Authors

• Jinnan Ou, From the Department of Nursing (Ou, Li, Zhao), Respiratory Care Unit (Chen), Department of Respiratory (Nie), Central South University, Changsha, Hunan, China
• Huaying Chen, From the Department of Nursing (Ou, Li, Zhao), Respiratory Care Unit (Chen), Department of Respiratory (Nie), Central South University, Changsha, Hunan, China
• Lezhi Li, From the Department of Nursing (Ou, Li, Zhao), Respiratory Care Unit (Chen), Department of Respiratory (Nie), Central South University, Changsha, Hunan, China
• Liping Zhao, From the Department of Nursing (Ou, Li, Zhao), Respiratory Care Unit (Chen), Department of Respiratory (Nie), Central South University, Changsha, Hunan, China
• Na Nie, From the Department of Nursing (Ou, Li, Zhao), Respiratory Care Unit (Chen), Department of Respiratory (Nie), Central South University, Changsha, Hunan, China

Abstract

Objectives: To estimate the benefits of non-invasive ventilation (NIV) used immediately after planned postextubation in patients with chronic respiratory disorders. Methods: Cochrane Library, PubMed, the Chinese BioMedical Literature Database of clinical trials (CBD) and Embase were searched for pertinent studies by 2 trained investigators. Pooled odds ratios and 95% confidence intervals (CIs) were calculated by employing both fixed-effects and random-effects models. Results: Eight studies enrolling 736 patients were included in the meta-analysis. Compared with general oxygen therapy, NIV used immediately after planned extubation in patients with chronic respiratory disease reduced the reintubation rate ( p =0.02), ventilator-associated pneumonia (VAP) incidence rate ( p =0.000), and ICU mortality ( p =0.002) and increased the level of PO2 ( p =0.03). Conclusion: Non-invasive ventilation used immediately after planned extubation seems to be advantageous for decreasing the reintubation rate, VAP incidence, and ICU death rate in patients with chronic respiratory disease.

Article Type

Review

First Page

131

Last Page

136

Recommended Citation

Ou, Jinnan; Chen, Huaying; Li, Lezhi; Zhao, Liping; and Nie, Na (2018) "The role of non-invasive ventilation used immediately after planned extubation for adults with chronic respiratory disorders," Saudi Medical Journal: Vol. 39: Iss. 2, Article 4.
DOI: https://doi.org/10.15537/smj.2018.2.21942