A limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine

Authors

• Fahdah Alokaily, From the Division of Rheumatology (Alokaily, Alrashidi), Department of Medicine; from the Department of Psychiatry (AlKathiri R), Prince Sultan Military Medical City, from the College of Medicine (AlKathiri S), King Saud University, Riyadh, Kingdom of Saudi Arabia.
• Reem AlKathiri, From the Division of Rheumatology (Alokaily, Alrashidi), Department of Medicine; from the Department of Psychiatry (AlKathiri R), Prince Sultan Military Medical City, from the College of Medicine (AlKathiri S), King Saud University, Riyadh, Kingdom of Saudi Arabia.
• Sarah AlKathiri, From the Division of Rheumatology (Alokaily, Alrashidi), Department of Medicine; from the Department of Psychiatry (AlKathiri R), Prince Sultan Military Medical City, from the College of Medicine (AlKathiri S), King Saud University, Riyadh, Kingdom of Saudi Arabia.
• Seham Alrashidi, From the Division of Rheumatology (Alokaily, Alrashidi), Department of Medicine; from the Department of Psychiatry (AlKathiri R), Prince Sultan Military Medical City, from the College of Medicine (AlKathiri S), King Saud University, Riyadh, Kingdom of Saudi Arabia.

Abstract

This is a case report of a 31-year-old lady who is known to have ulcerative colitis for 15 years and was on mesalazine. She presented with periorbital swelling, sinusitis, epistaxis, and was found to have positive anti-neutrophil cytoplasmic antibody and anti-proteinase-3 of a high titer. Biopsy from the maxillary sinus showed chronic non-specific inflammation and biopsy from the periorbital fat revealed inflammation and granulomatous changes. She had no other organ involvement. She was diagnosed with a limited form of granumatosis and polyangiitis and treated with methotrexate and prednisolone. The symptoms disappeared after treatment.

Article Type

Case Report

First Page

105

Last Page

107

Recommended Citation

Alokaily, Fahdah; AlKathiri, Reem; AlKathiri, Sarah; and Alrashidi, Seham (2022) "A limited form of granulomatosis with polyangiitis in an ulcerative colitis patient receiving sulfasalazine," Saudi Medical Journal: Vol. 43: Iss. 1, Article 13.
DOI: https://doi.org/10.15537/smj.2022.43.1.20210914