Effects of different fresh gas flows on carboxyhemoglobin levels: non-invasive carbon monoxide monitoring: A randomized clinical trial

Authors

• Bengü G. Köksal, From the Department of Anesthesiology and Reanimation, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.
• Gamze Küçükosman, From the Department of Anesthesiology and Reanimation, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.
• Pişkin Özcan, From the Department of Anesthesiology and Reanimation, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.
• Çağdaş Baytar, From the Department of Anesthesiology and Reanimation, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.
• Keziban Bollucuoğlu, From the Department of Anesthesiology and Reanimation, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.
• Rahşan D. Okyay, From the Department of Anesthesiology and Reanimation, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.
• Hilal Ayoğlu, From the Department of Anesthesiology and Reanimation, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.

Abstract

Objectives: To observe the effect of different fresh gas flows (FGF) on carboxyhemoglobin (COHb) levels non-invasively and continuously and to determine the contribution of the smoking status to intraoperative carbon monoxide (CO) accumulation and respiratory complications. Methods: A total of 64 patients were included in the study. Carboxyhemoglobin level was monitored non-invasively from the fingertip. Patients were divided into 2 according to the FGF as low-flow anesthesia (LFA; Group L) and high flow anesthesia (Group H). Each group was divided again into 2 groups as smokers and non-smokers. Carboxyhemoglobin and and the respiratory complications that occurred in the post-anesthesia care unit were recorded. Results: The mean COHb values were significantly higher in Group L between 30th and 210th minutes. Furthermore, in Group L, intraoperative COHb levels were significantly higher in smokers compared to non-smokers in all periods. In group H, no difference was observed between smokers and non-smokers in terms of COHb levels after 60 minutes and also preoperative COHb levels of the patients developed respiratory complication was higher. Conclusion: If the CO 2 absorbent is properly preserved in patients who are administered LFA, there will be no risk of CO accumulation even in chronic smokers. ClinicalTrials.gov REG. No.: NCT04832256

Article Type

Research Article

First Page

891

Last Page

898

Recommended Citation

Köksal, Bengü G.; Küçükosman, Gamze; Özcan, Pişkin; Baytar, Çağdaş; Bollucuoğlu, Keziban; Okyay, Rahşan D.; and Ayoğlu, Hilal (2022) "Effects of different fresh gas flows on carboxyhemoglobin levels: non-invasive carbon monoxide monitoring: A randomized clinical trial," Saudi Medical Journal: Vol. 43: Iss. 8, Article 4.
DOI: https://doi.org/10.15537/smj.2022.43.8.20220424