Macrophage activation syndrome induced by Staphylococcus Epidermidis in a pediatric patient with cystic fibrosis and familial Mediterranean fever

Authors

• Sanem Eryilmaz Polat, From the Department of Pediatrics, Division of Pediatric Pulmonology, Ankara City Hospital, Ankara, Turkey.
• Salih Uytun, From the Department of Pediatrics, Division of Pediatric Pulmonology, Ankara City Hospital, Ankara, Turkey.
• Işıl Bilgiç, From the Department of Pediatrics, Division of Pediatric Pulmonology, Ankara City Hospital, Ankara, Turkey.
• Gokcen D. Tuğcu, From the Department of Pediatrics, Division of Pediatric Pulmonology, Ankara City Hospital, Ankara, Turkey.

Abstract

Staphylococcus epidermidis (S. epidermidis) is the most frequently isolated member of the coagulase-negative staphylococci, which colonizes the skin and mucous membranes of the human body. Despite being a component of the normal flora, S. epidermidis can act as an opportunistic pathogen and is frequently implicated in both bacterial and nosocomial infections. Macrophage activation syndrome (MAS) is a rare but potentially fatal disease that occurs as a result of increased activation and proliferation of T lymphocytes and macrophages in response to infections and immune mediated diseases. It is very rare in patients with cystic fibrosis. Here we report a case of an 8-year-old girl with cystic fibrosis and familial Mediterranean fever who developed MAS after contracting a S. epidermidis infection.

Article Type

Case Report

First Page

1061

Last Page

1064

Recommended Citation

Polat, Sanem Eryilmaz; Uytun, Salih; Bilgiç, Işıl; and Tuğcu, Gokcen D. (2023) "Macrophage activation syndrome induced by Staphylococcus Epidermidis in a pediatric patient with cystic fibrosis and familial Mediterranean fever," Saudi Medical Journal: Vol. 44: Iss. 10, Article 15.
DOI: https://doi.org/10.15537/smj.2023.44.10.20230201