Abstract
ABSTRACT Objectives: To measure the gender differences in patient-reported outcomes and cardiac symptoms in patients with acute coronary syndrome (ACS) at King Khalid University Hospital in Riyadh, Saudi Arabia. Methods: A cross-sectional study was conducted on 240 randomly selected ACS patients aged ≥18 years. Data were collected using validated questionnaires, including Patient-reported outcomes measures, the Rose Dyspnea Scale, Patient Health Questionnaire, and Seattle Angina Questionnaire. Multiple linear regression analysis was conducted to identify factors associated with quality of life (QoL). Results: The study included 60% males and 40% females. Females reported significantly lower global physical health scores (11.62 [±2.49] versus (vs) 13.68 [±2.68], p =0.00), higher dyspnea symptoms (2.61 [±1.41] vs 1.55 [±1.51], p =0.00), and more physical limitation (43.2 [±31.8] vs 55.19 [±33.96], p =0.02). Multiple linear regression analysis showed female gender was associated with a decline in physical health (-0.33 [-2.42, -1.00]), increased dyspnea symptoms (0.30 [0.55, 1.37]), higher depression scores (0.14 [0.004, 0.87]), a decline in SAQ physical activity [-0.19 (-23.68, -2.60)] and summary scores [-0.14 (-11.34, -.04)]. Older age and lower income were also significantly associated with poorer QoL outcomes. Conclusion: Female gender, advanced age, and lower income were associated with worse patient-reported outcomes in ACS patients. Healthcare providers should consider these disparities to improve management strategies and QoL in this population.
Article Type
Research Article
First Page
388
Last Page
397
Recommended Citation
Alosaimi, Sultan; Alqarni, Abdullah; Alkalifah, Turki; Aldaijy, Mansor; Alghamdi, Nawaf; Altalhah, Abdulltaif; Kazi, Ambreen; and Alharbi, Waleed
(2025)
"Gender differences in patient-reported outcomes and cardiac symptoms in patients with acute coronary syndrome in Riyadh, Saudi Arabia,"
Saudi Medical Journal: Vol. 46:
Iss.
4, Article 10.
DOI: https://doi.org/10.15537/smj.2025.46.20240735