•  
  •  
 

Elshazly Abdulkhalik, Department of Cardiology, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia AND Department of Cardiology, Al Azhar University, Cairo, Egypt
Nagat Ibrahim, Department of Gastroenterology, Hepatology, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia
Selim Sidhom, Department of Cardiology, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia
Hesham H Alqurashi, Department of Gastroenterology, Hepatology, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia
Khaled Alghashmari, Department of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia
Muhammad Alotaibi, Department of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia
Ahmed Alqurashi, Department of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia
Moath Alzahrani, Department of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia
Shahad Alqahtani, Department of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia
Abdulaziz Alshalan, Department of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia
Nouran Althumali, Department of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia
Mazen Aljohani, Department of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia
Saud Alzahrani, Department of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia
Haidi Karam-Allah Ramadan, Department of Tropical Medicine and Gastroenterology, Faculty of Medicine, Assiut University, Assiut, EgyptFollow

Abstract

Objectives: To determine the influence of metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and hepatic fibrosis on the pattern and management of patients who had acute coronary syndrome (ACS).

Methods: Retrospective records of patients with ACS included demographic, electrocardiographic, and laboratory data of platelets count, glycated hemoglobin, lipogram, liver and cardiac enzymes. Ultrasound was used to evaluate fatty liver. Coronary angiography data included the number, site and percentage of the coronary arteries occluded. The type and outcome of treatment of ACS were recorded. Laboratory markers were measured to evaluate fibrosis.

Results: The study recruited 259 patients, and the majority were males. MASLD was detected in 123 (47.5%). The ST segment-elevation myocardial infarction (STEMI) was reported in 42.9% and non-STEMI (NSTEMI) in 30.1%. MASLD patients had frequent STEMI (38.2%) and NSTEMI (31.7%) with more involvement of left main coronary artery (10.6%). Patients with MASLD and higher fibrosis showed involvement of multiple coronary arteries and needed revascularization but without significant difference from non-MASLD. Left anterior descending and right coronary arteries were significantly involved in higher fibrosis.

Conclusion: STEMI and NSTEMI were frequent in MASLD. People with MASLD and hepatic fibrosis had more incidence of occlusion of multiple coronary arteries and needed cardiac intervention.

Article Type

Original Study

First Page

79

Last Page

86

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Download

Share

COinS